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Maria F M Braga Selected Research

tezampanel

11/2020Electroencephalographic analysis in soman-exposed 21-day-old rats and the effects of midazolam or LY293558 with caramiphen.
10/2018Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats.
1/2018Comparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric Population.
11/2017Susceptibility to Soman Toxicity and Efficacy of LY293558 Against Soman-Induced Seizures and Neuropathology in 10-Month-Old Male Rats.
2/2015LY293558 prevents soman-induced pathophysiological alterations in the basolateral amygdala and the development of anxiety.
1/2013Efficacy of the GluK1/AMPA receptor antagonist LY293558 against seizures and neuropathology in a soman-exposure model without pretreatment and its pharmacokinetics after intramuscular administration.
2/2011The GluK1 (GluR5) Kainate/{alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist LY293558 reduces soman-induced seizures and neuropathology.

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Maria F M Braga Research Topics

Disease

16Seizures (Absence Seizure)
11/2020 - 08/2009
16Status Epilepticus (Complex Partial Status Epilepticus)
11/2020 - 02/2008
3Mental Disorders (Mental Disorder)
02/2014 - 10/2004
3Epilepsy (Aura)
02/2011 - 02/2008
2Body Weight (Weight, Body)
10/2018 - 11/2017
2Anxiety Disorders (Anxiety Disorder)
01/2018 - 09/2014
1Rhinorrhea
10/2018
1Tremor (Tremors)
10/2018
1Miosis
10/2018
1Atrophy
01/2018
1Brain Concussion (Cerebral Concussion)
01/2018
1Chronic Disease (Chronic Diseases)
01/2018
1Contusions
01/2018
1Organophosphate Poisoning
03/2016
1Cognitive Dysfunction
11/2015
1Alzheimer Disease (Alzheimer's Disease)
11/2013
1Schizophrenia (Dementia Praecox)
11/2013
1Respiratory Insufficiency (Respiratory Failure)
01/2013
1Pain (Aches)
02/2011
1Traumatic Brain Injuries (Traumatic Brain Injury)
02/2008
1Stroke (Strokes)
02/2008
1Temporal Lobe Epilepsy
02/2008

Drug/Important Bio-Agent (IBA)

16Nerve AgentsIBA
11/2020 - 09/2009
11SomanIBA
11/2020 - 09/2010
7tezampanelIBA
11/2020 - 02/2011
5Anticonvulsants (Antiepileptic Drugs)IBA
10/2018 - 08/2009
5AcetylcholinesteraseIBA
10/2018 - 09/2013
4Diazepam (Valium)FDA LinkGeneric
11/2020 - 01/2010
3AtropineFDA LinkGeneric
03/2016 - 01/2013
3Kainic Acid Receptors (Kainate Receptor)IBA
11/2014 - 10/2004
3AcidsIBA
01/2013 - 08/2009
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
11/2020 - 11/2015
2alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
11/2020 - 02/2011
2caramiphenIBA
11/2020 - 10/2018
2OximesIBA
03/2016 - 01/2013
21H-tetrazole (tetrazole)IBA
01/2013 - 02/2011
2Carboxylic AcidsIBA
01/2013 - 02/2011
2GABA-A Receptors (GABA(A) Receptor)IBA
03/2011 - 01/2010
1Midazolam (Versed)FDA LinkGeneric
11/2020
1Muscarinic AntagonistsIBA
11/2020
1Acetylcholine (Acetylcholine Chloride)FDA Link
10/2018
1BenzodiazepinesIBA
01/2018
1alpha-Linolenic Acid (Linolenic Acid)IBA
01/2018
1Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
01/2017
1OrganophosphatesIBA
01/2017
1Muscarinic M1 ReceptorIBA
01/2017
1N- (3- oxo- 3- (4- (pyridin- 4- yl)piperazin- 1- yl)propyl)benzo(c)(1,2,5)thiadiazole- 4- sulfonamideIBA
01/2017
1pralidoxime (Protopam Chloride)FDA Link
03/2016
1Obidoxime Chloride (Obidoxime)IBA
03/2016
1Paraoxon (E600)IBA
03/2016
11- (2- amino- 2- carboxyethyl)- 3- (2- carboxybenzyl)pyrimidine- 2,4- dioneIBA
11/2014
1willardiineIBA
11/2014
1Cholinergic Agents (Cholinergics)IBA
09/2014
1Acid Sensing Ion ChannelsIBA
02/2014
1Anti-Anxiety Agents (Anxiolytics)IBA
11/2013
1NicotineFDA Link
11/2013
1asoxime chloride (H16)IBA
01/2013
1AMPA Receptors (AMPA Receptor)IBA
01/2013
1ConvulsantsIBA
03/2011
1cyclonite (RDX)IBA
03/2011
1Kainic Acid (Kainate)IBA
02/2011
1fluoro-jade CIBA
09/2010
1Topiramate (Topamax)FDA LinkGeneric
08/2009
1sulfamic acid (ammonium sulfamate)IBA
08/2009
1Gluk1 kainate receptorIBA
08/2009

Therapy/Procedure

1Therapeutics
01/2018
1Intranasal Administration
03/2016
1Emergency Treatment
02/2011
1Drug Therapy (Chemotherapy)
02/2008